Food & Alcohol Interaction Protocol
How diet impacts this medicine's absorption and efficacy
Food may delay absorption of aceclofenac but does not significantly affect overall bioavailability. Paracetamol absorption may be delayed by food.
Chronic alcohol consumption increases the risk of paracetamol hepatotoxicity. Alcohol may also increase the risk of gastrointestinal bleeding with aceclofenac.
What is this Medicine Used For?
Primary clinical indications and therapeutic purpose
This combination is primarily used for the symptomatic treatment of acute and chronic pain associated with musculoskeletal disorders such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It is also effective for dental pain, postoperative pain, and dysmenorrhea. The antipyretic property of paracetamol makes it useful for fever associated with pain conditions.
Known Side Effects & Cautions
Common symptoms to monitor while taking this drug
["Nausea","Vomiting","Abdominal pain","Dyspepsia","Diarrhea","Constipation","Dizziness","Headache","Rash","Pruritus"]
Doctor Safety Advice & Precautions
Use with caution in patients with a history of gastrointestinal disease (ulcerative colitis, Crohn's disease), renal impairment, hepatic impairment, cardiovascular disease, hypertension, asthma, or bleeding disorders. Avoid concomitant use with other NSAIDs or paracetamol-containing products. Monitor liver function tests during prolonged use. Paracetamol overdose can cause severe liver damage; maximum daily dose should not exceed 4 g in adults. Elderly patients are at increased risk of side effects.
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